Treatment and Outcome of Stiff-Man Syndrome
نویسندگان
چکیده
منابع مشابه
Jerking stiff-man syndrome.
A female patient had permanent axial muscular rigidity similar to the "stiff-man syndrome", together with axial myoclonus triggered by stretch reflexes and by supramaximal stimulation of the supraorbital nerve. The disorder responded to treatment with diazepam and baclofen. This disorder bore a marked similarity to the so-called "jerking stiff-man syndrome".
متن کاملStiff man syndrome and related conditions.
The stiff man syndrome (SMS) and its variants, focal SMS, stiff limb (or leg) syndrome (SLS), jerking SMS, and progressive encephalomyelitis with rigidity and myoclonus (PERM), appear to occur more frequently than hitherto thought. A characteristic ensemble of symptoms and signs allows a tentative clinical diagnosis. Supportive ancillary findings include (1) the demonstration of continuous musc...
متن کاملThe 'stiff man syndrome' in a boy.
In October, 1958, a Chinese boy, aged 7 years, was transferred to the Children's Unit with a diagnosis of recurrent tetanus. According to the mother, he had been ill intermittently since 1957 when he was first admitted to hospital complaining of stiffness of the body and inability to open his mouth. He apparently recovered from this illness, but was readmitted on two further occasions with simi...
متن کاملStiff man syndrome with invasive thymic carcinoma.
Stiff man syndrome is a rare disease characterized by painful chronic spasms in the muscle and skeletal system. This syndrome is an autoimmune neurologic disorder which is associated with thymoma. We treated a 32-year-old male patient with a type C thymoma (based on the World Health Organization classification) who had stiff man syndrome. The patient underwent an extended thymectomy which broug...
متن کاملAutoimmunity to Gephyrin in Stiff-Man Syndrome
Stiff-Man syndrome (SMS) is a rare disease of the central nervous system (CNS) characterized by chronic rigidity, spasms, and autoimmunity directed against synaptic antigens, most often the GABA-synthesizing enzyme glutamic acid decarboxylase (GAD). In a subset of cases, SMS has an autoimmune paraneoplastic origin. We report here the identification of high-titer autoantibodies directed against ...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 2012
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-26-3-7